Mathematical modelling for determining intestinal permeability using polyethyleneglycol.
نویسندگان
چکیده
منابع مشابه
Intestinal permeability to polyethyleneglycol and sugars: a re-evaluation.
1. Previous studies have indicated that the permeability of polyethyleneglycol across the human intestine is anomalously high in comparison with the permeability of sugars with similar molecular mass. In consequence it has been proposed that two or more distinct mechanisms must exist for the translocation of these classes of molecule or, alternatively, that the molecular parameter determining r...
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Ileal permeability to different sized polyethyleneglycols (590-942 dalton PEG) was investigated peroperatively in 11 patients with Crohn's disease and seven with colonic carcinoma. A 15 cm ileal segment was converted into a tied loop, in which the PEG's were deposited. Absorption from the ileal segment was then measured as six-hour urinary recovery of the PEg dose. Polyethyleneglycol absorption...
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ژورنال
عنوان ژورنال: Gut
سال: 1984
ISSN: 0017-5749
DOI: 10.1136/gut.25.4.428